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Fatal encephalopathy complicating lymphoid interstitial pneumonia
  1. Michael Jefferson,
  2. D. Riddoch1,
  3. W. Thomas Smith
  1. Department of Neurology, United Birmingham Hospitals
  2. Department of Pathology, University of Birmingham


    The case is reported of a young woman who suffered from lymphoid interstitial pneumonia. Involvement of the brain by what appeared to be an identical pathological process led to her death, and the orbital tissues were also involved at one stage. The cause of this condition is unknown, but the hypotheses are put forward that it may represent one facet of delayed hypersensitivity or that a slow virus is the responsible aetiological agent. Although lymphoid interstitial pneumonia has previously been reported as an isolated entity, the evidence from this case suggests that it might represent part of pluri-systemic disease.

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