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Biochemical studies in Tanzanian patients with ataxic tropical neuropathy
  1. W. J. Makene,
  2. J. Wilson1
  1. Faculty of Medicine, University College, Dar Es Salaam, Tanzania, London
  2. The M.R.C. Clinical Genetics Research Unit, Institute of Child Health, London
  3. Institute of Neurology, London

    Abstract

    Data on thiocyanate and vitamin B12 concentrations in plasma from Tanzanian patients with ataxic tropical neuropathy are presented and support the hypothesis that, as in Nigeria, the condition may result from chronic exposure to cyanide or cyanogens from a diet including large amounts of cassava.

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    Footnotes

    • 1 Requests for reprints: J. Wilson, M.R.C. Clinical Genetics Research Unit, National Hospital, Queen Square, London WC1N 3BG.