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Myositis in father and daughter
  1. R. M. Lewkonia1,
  2. P. H. Buxton
  1. Royal Southern Hospital, Liverpool
  2. The Neuropathology Laboratory, Regional Department of Medical and Surgical Neurology, Walton Hospital, Liverpool


    The occurrence of myositis in a father and his daughter is reported. The daughter's illness resembled childhood dermatomyositis and progressed to systemic involvement and death less than four years from the onset of symptoms. In the case of the father the illness followed the course of adult polymyositis and there was little evidence of systemic involvement. The immunological and genetic significance of the two cases is discussed.

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    • 1 Present address: Nuffield Unit of Medical Genetics, Department of Medicine, University of Liverpool.