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Motor nerve conduction velocity in peroneal muscular atrophy: evidence for genetic heterogeneity
  1. P. K. Thomas,
  2. D. B. Calne
  1. Royal Free, Royal National Orthopaedic, London
  2. Hammersmith Hospitals, London


    Measurements of motor nerve conduction velocity are reported in 88 subjects from 20 families in which a clinical diagnosis of peroneal muscular atrophy had been made in the index cases. The values display a bimodal distribution. The majority of cases show a substantially reduced conduction velocity, a smaller group displaying velocities within the normal range or only slightly decreased. This difference was demonstrated to have a genetic basis.

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