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Lumbosacral agenesis: management and embryological implications
  1. R. J. Ignelzi1,
  2. R. A. W. Lehman
  1. Department of Neurosurgery, University of Colorado Medical Center, Denver, Colorado, U.S.A.


    Rectal biopsy in a case of lumbosacral agenesis showed the presence of autonomic nerve elements normally supplied by spinal levels distal to the agenesis. Certain implications are suggested regarding the embryogenesis of this condition from data about the development of neural, bony, and muscular elements. Recommendations regarding management are given.

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    • 1 Reprint requests: Dr R. J. Ignelzi, Neurosurgery Section, V. A. Hospital, 3350 La Jolla Village Drive, San Diego, Calif. 92161, U.S.A.