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An unusual intranuclear structure (? viral nucleocapsid) in the brain in subacute sclerosing panencephalitis
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  1. A. D. Dayan1,
  2. Swati Majumdar,
  3. W. Hughes,
  4. K. W. G. Heathfield
  1. Department of Neuropathology, The National Hospitals, London
  2. Oldchurch Hospital, Romford

    Abstract

    A brain biopsy was examined from a 7 year old boy with subacute sclerosing panencephalitis. Intranuclear deposits of measles antigens were demonstrated in parenchymal cells by immunofluorescence. Electron microscopy showed viral nucleocapsids in nucleoliform inclusions and unusual rod-like intranuclear structures which resemble structures previously described only in tissue cultures infected with measles virus.

    http://dx.doi.org/10.1136/jnnp.37.2.201

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      Footnotes

      • ↵1 Present address: Wellcome Research Laboratories, Langley Court, Beckenham, Kent BR3 3BS.