Article Text

Download PDFPDF

Focal reflex myoclonus
  1. G. G. Sutton,
  2. R. F. Mayer
  1. Department of Neurology, University of Maryland School of Medicine, Baltimore, Maryland 21201, U.S.A.


    In a patient with reflex myoclonus limited to the right side of the body, stimulation of the right median nerve in the index finger or wrist elicited a very large somatosensory evoked response (SER) and a long loop C reflex which represents an electrically evoked myoclonic response. It is suggested that the pathway for the C reflex is through peripheral nerve, dorsal funiculus of spinal cord, contralateral VP nucleus of thalamus, sensorimotor cortex, corticospinal tract, and anterior horn cell. The large SER, C reflex, and myoclonic jerks are presumed to result from a release effect causing increased excitability at central synapses along this pathway. The patient presented has a large atrophic vascular lesion involving the left frontotemporoparietal region and involvement of pathways through the right superior cerebellar peduncle to account for the neural dysfunction.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


    • 1 Presented at the Society for Neuroscience, 29 October 1971, Washington, D.C. Supported in part from research grants (MH1-7006 and NSO6779) from the National Institutes of Health, U.S. Public Health Services.