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Relation of measles virus to encephalitogenic factor with reference to the aetiopathogenesis of multiple sclerosis
  1. J. R. McDermott,
  2. E. J. Field1,
  3. E. A. Caspary
  1. Medical Research Council Demyelinating Diseases Unit, Newcastle General Hospital, Newcastle upon Tyne


    A combination of affinity chromatography with the macrophage electrophoretic migration (MEM) test has been used to study the antigenic similarities between encephalitogenic factor (EF) and measles virus. These have determinant(s) sufficiently closely related to account for the elevated level of circulating antibody to measles in multiple sclerosis.

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    • 1 Present address: Institute of Pathology, Newcastle General Hospital, Newcastle upon Tyne.

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