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Absent vestibulo-ocular reflexes and acute supratentorial lesions
  1. Michael Rosenberg2,
  2. James Sharpe,
  3. William F. Hoyt
  1. Neuro-ophthalmology Unit, Departmenta of Neurological Surgery and Neurology, University of California School of Medicine, San Francisco, California, U.S.A.


    Loss of vestibulo-ocular reflexes occurred in two patients with acute supratentorial lesions who received therapeutic doses of anticonvulsant drugs. There was no clinical or angiographic evidence of focal brain-stem damage. Absence of vestibulo-ocular reflexes is attributed to a combination of acute cerebral damage and anticonvulsant drugs. The loss of these reflexes in patients with acute cerebral lesions cannot be interpreted as evidence of irreversible brain-stem injury.

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    • 2 Reprint requests: Dr M. A. Rosenberg, University of Illinois Eye and Ear Infirmary, 1855 W. Taylor St., Chicago, Illinois, U.S.A. (Accepted 17 June 1974).

    • 1 This work was supported in part by a Heed Ophthalmic Foundation Grant (M. Rosenberg); Ontario Ministry of Health Fellowship (J. Sharpe); and U.S.P.H.S. N.I.H. Training Grant EY 00083-02 (W.F. Hoyt).

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