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Mental change as an early feature of multiple sclerosis
  1. A. C. Young,
  2. J. Saunders,
  3. J. R. Ponsford
  1. Department of Neurology, Churchill Hospital and Radcliffe Infirmary, Oxford


    Five patients with mental change as a prominent and early feature of an illness which appeared to be multiple sclerosis are reported. All the patients had in addition clinical signs of predominant brain stem involvement and the cerebrospinal fluid findings were similar. It is emphasised that mental change may be an early feature of multiple sclerosis even in those patients in whom the onset of the disease is insidious.

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