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Uptake of bleomycin by human brain tumours
  1. T. Hayakawa2,
  2. Y. Ushio,
  3. K. Morimoto,
  4. H. Hasegawa,
  5. H. Mogami,
  6. K. Horibata
  1. Department of Neurosurgery, Osaka University Medical School, Osaka, Japan
  2. Institute of Microbial Chemistry, Tokyo, Japan


    The uptake of bleomycin (BLM) by various types of brain tumours after intravenous or intrathecal administration was investigated by bioassay in 67 patients. The correlation between the BLM distribution and the type and characteristics of brain tumours was studied.

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    • 2 Address for reprint requests: Dr Toru Hayakawa, Department of Neurosurgery, Osaka University Hospital, 3-Dojima-hamadori, Fukushima-ku, Osaka, Japan.

    • 1 This work was supported in part by grants-in-aid for Fundamental Scientific Research from the Ministry of Public Welfare and from the Ministry of Education.