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Sarcoid-like disorder of the intracranial optic nerve
  1. L. Frisén,
  2. S. Lindgren,
  3. B. J. L. MacGregor,
  4. S. Stattin
  1. Department of Ophthalmology, University of Göteborg, Sweden
  2. Department of Neurosurgery, University of Göteborg, Sweden
  3. Department of the Laboratory of Neuropathology, University of Göteborg, Sweden
  4. Department of the Section of Neuroradiology, University of Göteborg, Sweden

    Clinicopathological report of two cases


    Two cases with a sarcoid-like disorder apparently restricted to the intracranial optic nerve and the adjacent dura mater are described, doublilng the number of reported cases. In both instances there were unilateral visual loss and unusual radiographic changes in the optic canal area. Biopsy samples showed localised infiltration of tissues with non-caseating tubercles containing epithelioid and multinucleated giant cells.

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    Clinicopathological report of two cases