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Toxic encephalopathy due to ingestion of bismuth salts: clinical and EEG studies of 45 patients
  1. V. Supino-Viterbo,
  2. C. Sicard,
  3. M. Risvegliato,
  4. G. Rancurel,
  5. A. Buge
  1. Neurosurgery EEG Laboratory, Salpétrière Hospital, Paris, France
  2. Department of EEG, Salpétrière Hospital, Paris, France
  3. Department of Clinical Neurology, Salpétrière Hospital, Paris, France
  4. Department of Clinical Neurology, Bicêtre Hospital, Paris, France


    Forty-five patients taking bismuth subnitrate orally for therapeutic reasons were admitted to hospital with a myoclonic encephalopathy of acute onset. The clinical features were similar, mostly with mental confusion, disorder of walking and standing, dysarthria, and myoclonic jerks. In 31 cases the EEG showed a characteristic pattern, not previously recognised, which assisted differential diagnosis.

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