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Histocompatibility antigens (HLA) in multiple sclerosis in Iran.
  1. J Lotfi,
  2. B Nikbin,
  3. I Derakhshan,
  4. Z Aghai,
  5. F Ala


    Thirty-five patients (19 male and 16 female) with clinically definite multiple sclerosis and 100 healthy control subjects were studied for the A and B locus of the HLA system. A significant increase of HLA A3 and A11 of the A locus and B7 of the B locus was observed in patients with multiple sclerosis compared with controls. An increase of antigen A3 was also observed in eight cases of probable multiple sclerosis. A significant increase of both A3 and B7 was observed in patients with multiple sclerosis.

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