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Contrast-enhanced lesions on computerised tomography in multiple sclerosis.
  1. A E Harding,
  2. E W Radue,
  3. A M Whiteley


    Two patients are described in whom computerised tomography revealed contrast-enhanced lesions in the early stages of multiple sclerosis. Such lesions may be differentiated from tumours by their transient nature, lack of space-occupying effect, and localisation in the white matter. Contrast enhancement in demyelinating disease is probably related to local breakdown of the blood-brain barrier.

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