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Crural hypertrophy associated with centronuclear myopathy
  1. P. Bill,
  2. G. Cole,
  3. N. S. F. Proctor,
  4. D. Saffer,
  5. A. Botes
  1. Department of Neurology, Baragwanath Hospital, Transvaal, Johannesburg, South Africa
  2. Neuropathology Unit, Department of Anatomical Pathology, School of Pathology of the University of the Witwatersrand, Johannesburg, South Africa
  3. Electron Microscopy Unit, Department of Anatomical Pathology, School of pathology of the University of the Witwatersrand, Johannesburg, South Africa
  4. South African Institute for Medical Research, Johannesburg, South Africa

    Abstract

    A case of centronuclear myopathy of adult onset with striking hypertrophy of lower limb muscles in a black South African man is described with details of the light microscopic, histochemical, and ultrastructural features. The association of hypertrophied muscles with centronuclear myopathy has not to our knowledge been reported previously and it is felt that this may be a variant of the condition.

    https://doi.org/10.1136/jnnp.42.6.542

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