This report describes a 46 year old woman having both thymoma and myotonic dystrophy. Laboratory studies revealed an anterior mediastinal mass, lymphocytopenia, anergic reaction to dinitrochlorobenzene and electrophysiological evidence of myotonia. Postmortem examination disclosed a thymoma with predominant proliferation of epithelial cells. This paper is the second necropsy report of myotonic dystrophy associated with thymoma.
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