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Research Article
Cerebrospinal fluid GABA levels in various neurological and psychiatric diseases.
  1. H Kuroda,
  2. N Ogawa,
  3. Y Yamawaki,
  4. I Nukina,
  5. T Ofuji,
  6. M Yamamoto,
  7. S Otsuki

    Abstract

    Cerebrospinal fluid gamma-aminobutyric acid (CSF-GABA) was analysed by radioreceptor assay in 16 normal controls and 84 patients with various neurological and psychiatric diseases. In patients with spinocerebellar degeneration, neuro-Behçet's syndrome and Parkinson's disease, CSF-GABA levels were decreased. On the other hand, increased CSF-GABA levels were detected in patients with meningitis.

    https://doi.org/10.1136/jnnp.45.3.257

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