A periodic EEG pattern very similar to the changes in Creutzfeldt-Jakob disease was seen in a case of anoxic encephalopathy. Necropsy revealed status spongiosus of the cerebral cortex. Generalised repetitive sharp transients in anoxic encephalopathy occur when the patient is comatose and carry a poor prognosis. They are not specific for Creutzfeldt-Jakob disease.
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