Article Text


"Painful legs and moving toes" associated with polyneuropathy.
  1. P Montagna,
  2. F Cirignotta,
  3. T Sacquegna,
  4. P Martinelli,
  5. G Ambrosetto,
  6. E Lugaresi
  1. Institute of Neurology, University of Bologna, Italy.


    Three patients showing clinical and electrophysiological evidence of peripheral neuropathy also suffered from the syndrome of "painful legs and moving toes". Polygraphic recordings during wakefulness and sleep were consistent with the hypothesis that pathological afferent discharges arising peripherally may induce, via the spinal cord, motor excitation and pain. A severe disruption of the pattern of sleep was found in all cases.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.