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Research Article
Action of tizanidine on responses of forearm flexors and extensors to torque disturbances.
  1. R Mackel,
  2. E E Brink,
  3. Y Nakajima

    Abstract

    The effects of tizanidine on the electromyographic responses of forearm flexors and extensors to torque disturbances were studied in normal subjects. Tizanidine had a strong depressive action on all the reflex responses, and on muscle background activity. It is concluded that the action on reflexes is not specific, but secondary to decreased spinal cord excitability.

    https://doi.org/10.1136/jnnp.47.10.1109

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