The results of a stereotactic thalamotomy in 11 patients with clinically definite multiple sclerosis and severe intention tremor are discussed. The operation produces a beneficial effect on the tremor and an improvement of arm function in most patients. The good results have often been counterbalanced by postoperative complications or progression of the disease. An operation may be considered, if the tremor lasts for at least a year, and if there is no serious cerebral atrophy or other relevant damage to CNS structures. The patient must be capable of giving informed consent.
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