Article Text

Download PDFPDF
Biochemical studies in mitochondrial encephalomyopathy.
  1. S Goda,
  2. S Ishimoto,
  3. I Goto,
  4. Y Kuroiwa,
  5. K Koike,
  6. M Koike,
  7. M Nakagawa,
  8. H Reichmann,
  9. S DiMauro
  1. Department of Neurology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.


    The alpha-keto acid dehydrogenase complex and its component enzymes, lactate dehydrogenase, pyruvate carboxylase, cytochrome c oxidase, succinate-cytochrome c reductase, NADH-cytochrome c reductase, and the concentration of cytochromes and enzymes of beta-oxidation in muscle from a patient with mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes were studied and no specific defect was found. These results raise the possibility that the mitochondrial changes in the patient may be secondary.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.