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Serotonin in tension headache.
  1. R Shukla,
  2. K Shanker,
  3. D Nag,
  4. M Verma,
  5. K P Bhargava
  1. Department of Neurology, King George's Medical College, Lucknow, India.


    Serotonin (5-hydroxytryptamine, 5-HT) is implicated in the pathogenesis of migraine; however, its role in tension headache has not yet been studied. The uptake of 5-HT by platelets in patients of tension headache was significantly higher compared with migraineurs as well as controls. The basal platelet 5-HT levels did not show a significant difference. The study implicates the role of serotonin in tension headache.

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