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McArdle's sign in multiple sclerosis.
  1. J H O'Neill,
  2. K R Mills,
  3. N M Murray
  1. National Hospital for Nervous Diseases, Queen Square, London, UK.


    A patient with multiple sclerosis is reported in whom neck flexion produced a reversible deterioration in gait and an increase in the degree of pyramidal weakness of the lower limbs. The name McArdle's sign is proposed.

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