Article Text

Download PDFPDF

Increased prolactin response to thyrotropin releasing hormone during migraine attacks.
  1. Y Papakostas,
  2. M Daras,
  3. M Markianos,
  4. C Stefanis


    Prolactin (PRL) has been associated with the pathogenesis of migraine, and various approaches have been used to investigate its role. In the present study, the PRL response to thyrotropin-releasing hormone (TRH) was evaluated in eight women migraineurs during an attack-free state and during a migraine attack. PRL baseline values were not different in the two states, and the same was true for the TSH responses to TRH. The PRL responses to TRH were, however, significantly higher during the attack, a finding that indicates a latent disturbance of the PRL-regulating systems in migraine, with a higher responsiveness during migraine attacks.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.