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Short-term stability of single motor unit recordings in motor neuron disease: a macro EMG study.
  1. R J Guiloff,
  2. H Modarres-Sadeghi,
  3. E Stålberg,
  4. H Rogers
  1. Department of Neurology, Westminster Hospital, London, UK.


    Thirty five individual macro EMG motor unit potentials in 13 patients with motor neuron disease were recorded every 15 minutes during a 2 hour period. No significant change in amplitude or area was seen in 15 control units in nine patients or in 20 units in 11 patients receiving RX77368 0.2-0.3 mg/kg. The findings provide no evidence for an action of this long acting TRH analogue on the peripheral territory of motor units in motor neuron disease.

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