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Does acute hyperglycaemia influence heat pain thresholds?
  1. A W Chan,
  2. I A MacFarlane,
  3. D R Bowsher,
  4. J C Wells
  1. Diabetic Clinic, Walton Hospital, Liverpool, UK.


    The influence of acute hyperglycaemia on pain sensation was assessed in eight young adult non-diabetic subjects. Acute hyperglycaemia was induced with IV glucose in a double blind fashion, with IV saline as a control. Pain thresholds were assessed by a painful heat stimulus delivered by a Marstock thermode on the thenar eminence. Heat pain thresholds did not significantly alter during either acute hyperglycaemia or the control saline infusion. Previous work demonstrating a lowering of electrical pain thresholds by hyperglycaemia has therefore not been confirmed using a natural painful stimulus.

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