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Effects of radiation therapy on neuropsychological functioning in patients with nasopharyngeal carcinoma.
  1. P W Lee,
  2. B K Hung,
  3. E K Woo,
  4. P T Tai,
  5. D T Choi
  1. Department of Psychiatry, University of Hong Kong.


    Sixteen patients who had a nasopharyngeal carcinoma (NPC) who were treated with radiation therapy were followed up after a median duration of 5.5 years and given a battery of neuropsychological tests. Results were compared with a comparable group of newly diagnosed NPC patients awaiting radiation therapy. The irradiated group was significantly poorer in overall IQ, non-verbal memory recall, and reported a substantially greater number of memory related complaints. These results contrast with the complacent general assumption that radiation therapy has a negligible effect on adult functioning.

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