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Chronic relapsing idiopathic polyneuropathy with primary axonal lesions.
  1. J Julien,
  2. C Vital,
  3. A Lagueny,
  4. X Ferrer,
  5. C Brechenmacher
  1. Department of Neurology, Hôpital du Haut-Levêque, Pessac, France.


    Idiopathic polyradiculoneuropathy with primary axonal lesions is rarely encountered. Two cases are reported with a chronic relapsing course and a fatal outcome. Neuropathological examination of biopsied peripheral nerve in the two patients and in a necropsy case showed loss of myelinated fibres, but neither active demyelination nor inflammatory cells were observed. Acute and chronic relapsing axonal polyradiculoneuropathies appear to be two clinical forms of a peculiar entity different from GBS.

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