You are here

Article Text

Article menu

PDF

Research Article
HLA antigens in multiple sclerosis of northern Spanish population.
  1. C López-Larrea,
  2. D F Uría,
  3. E Coto
  1. Inmunología, Hospital NS Covadonga, Oviedo, Spain.

    Abstract

    HLA-A, -B, -C, -DR, -DQ antigens were studied in 43 multiple sclerosis (MS) patients with clinically definite remittent sclerosis from Asturias (North Spain). The prevalence of HLA-B7, B7 and B27 were significantly increased in MS. HLA-B35 was under-represented in these patients. DR2 was increased but not significantly. No association with DQw1 was discovered. The existence of several susceptibility factors in the more common B7/DR2/DQw1 haplotype is discussed.

    http://dx.doi.org/10.1136/jnnp.53.5.434

    Statistics from Altmetric.com

      Request Permissions

      If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.