Article Text


Neuroleptic malignant syndrome and hypothyroidism.
  1. A P Moore,
  2. I A Macfarlane,
  3. L D Blumhardt
  1. Department of Neurological Science, University of Liverpool, Walton Hospital, Liverpool, United Kingdom.


    Two patients with primary hypothyroidism who developed neuroleptic malignant syndrome (NMS) are described. Thyroid disease might predispose to NMS by altering brain dopamine metabolism.

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