Article Text

Download PDFPDF
Normal P300 following extensive damage to the left medial temporal lobe.
  1. M D Rugg,
  2. C D Pickles,
  3. D D Potter,
  4. R C Roberts
  1. Wellcome Brain Research Group, Department of Psychology, University of St Andrews, UK.


    Event-related potentials (ERPs) were recorded during auditory and visual "oddball" tasks from a patient with a severe verbal memory deficit due to a low grade infiltrating glioma which involved the full extent of the left medial temporal lobe. In both sensory modalities, the patient's oddball-evoked P300s were symmetrical and of normal amplitude. These findings are difficult to reconcile with the hypothesis that the hippocampus, or any other medial temporal structure, makes a substantial contribution to the scalp P300.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.