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A double blind trial of botulinum toxin "A" in torticollis, with one year follow up.
  1. A P Moore,
  2. L D Blumhardt
  1. Department of Neurological Science, University of Liverpool, UK.


    A double blind placebo controlled crossover trial was performed of botulinum toxin "A" in 20 patients with spasmodic torticollis. There was a statistically significant benefit for those treated with toxin; 12 on toxin improved objectively, compared with four on placebo (p less than 0.04). After a follow up period of one year, 16 still seemed to benefit from repeated toxin injections. The main side effect was dysphagia, which appeared to be dose related in individual patients.

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