You are here

Article Text

Article menu
Download PDFPDF
Research Article
Apomorphine in treatment of Parkinson's disease: comparison between subcutaneous and sublingual routes.
  1. D Deffond,
  2. F Durif,
  3. M Tournilhac
  1. Clinique Neurologique, Hôpital Fontmaure, Chamalieres, France.

    Abstract

    The efficacy of two routes of apomorphine, subcutaneous (SC) and sublingual (SL), successively administered in 7 Parkinsonian patients with motor fluctuations, was compared in reducing the daily duration of "off" phases. The mean duration of SC and SL treatment was 7.7 and 6.8 months respectively. The mean time spent in "off" phase was 55% after SC and 68% after SL treatment. The mean time before turning "on" after an "off" period was 14 minutes after SC and 28 minutes after SL treatment. Two patients developed stomatitis after SL route. SL apomorphine may be helpful in the treatment of motor fluctuations in PD.

    https://doi.org/10.1136/jnnp.56.1.101

    Statistics from Altmetric.com

      Request Permissions

      If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.