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Successful treatment of childhood onset symptomatic dystonia with levodopa.
  1. N A Fletcher,
  2. P D Thompson,
  3. J W Scadding,
  4. C D Marsden
  1. University Department of Clinical Neurology, Institute of Neurology, London, UK.


    Three patients with childhood onset symptomatic dystonia responded to levodopa. None fulfilled criteria for a diagnosis of "dopa responsive dystonia" (Segawa's disease). One may have had athetoid cerebral palsy for almost 25 years. All obtained dramatic and sustained benefit from levodopa therapy. A therapeutic trial of levodopa is advised in all patients in whom dystonia has developed in childhood or early adult life, regardless of suspected aetiology or duration of symptoms.

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