Decreased N-acetyl-aspartate/choline ratio and increased lactate in the frontal lobe of patients with Huntington's disease: a proton magnetic resonance spectroscopy study.

L Harms; H Meierkord; G Timm; L Pfeiffer; A C Ludolph

doi:10.1136/jnnp.62.1.27

Article metrics

Research Article

Decreased N-acetyl-aspartate/choline ratio and increased lactate in the frontal lobe of patients with Huntington's disease: a proton magnetic resonance spectroscopy study.

Online download statistics by month:

Online download statistics by month: March 1999 to October 2024

	Abstract	Full	Pdf
Mar 1999	3	0	0
Apr 1999	1	0	0
May 1999	1	0	0
Oct 1999	1	0	0
Nov 1999	4	0	0
Dec 1999	1	0	0
Jan 2000	2	0	0
Feb 2000	2	0	0
Mar 2000	1	0	0
Apr 2000	1	0	0
May 2000	3	0	0
Jun 2000	1	0	0
Aug 2000	3	0	0
Oct 2000	2	0	0
Nov 2000	5	0	0
Dec 2000	1	0	1
Feb 2001	3	0	0
Mar 2001	4	0	0
Apr 2001	1	0	0
May 2001	1	0	0
Jun 2001	2	0	0
Jul 2001	1	0	0
Aug 2001	1	0	0
Oct 2001	2	0	0
Feb 2002	1	0	0
May 2002	1	0	0
Jun 2002	3	0	0
Jul 2002	3	0	0
Oct 2002	1	0	0
Nov 2002	1	0	0
May 2003	1	0	0
Jun 2003	2	0	0
Jul 2003	2	0	0
Sep 2003	3	0	0
Nov 2003	1	0	0
Dec 2003	3	0	0
Feb 2004	1	0	0
Mar 2004	1	0	0
Apr 2004	1	0	0
Jun 2004	3	0	0
Jul 2004	4	0	0
Aug 2004	6	0	0
Sep 2004	4	0	0
Oct 2004	3	0	0
Nov 2004	2	0	0
Dec 2004	4	0	0
Jan 2005	7	0	0
Feb 2005	9	0	0
Mar 2005	5	0	0
Apr 2005	3	0	0
May 2005	2	0	0
Jun 2005	1	0	0
Jul 2005	1	0	0
Aug 2005	2	0	0
Sep 2005	2	0	0
Oct 2005	5	0	0
Nov 2005	6	0	0
Dec 2005	1	0	0
Jan 2006	8	0	0
Feb 2006	4	0	0
Mar 2006	11	0	0
Apr 2006	5	0	0
May 2006	3	0	0
Jun 2006	5	0	0
Jul 2006	6	0	0
Aug 2006	3	0	0
Sep 2006	3	0	0
Oct 2006	4	0	0
Nov 2006	8	0	0
Dec 2006	6	0	0
Jan 2007	2	0	0
Feb 2007	5	0	0
Mar 2007	1	0	0
Apr 2007	9	0	0
May 2007	1	0	0
Jun 2007	3	0	0
Jul 2007	7	0	0
Aug 2007	4	0	0
Sep 2007	5	0	0
Oct 2007	7	0	0
Nov 2007	4	0	0
Dec 2007	8	0	0
Jan 2008	6	0	0
Feb 2008	4	0	0
Mar 2008	6	0	0
Apr 2008	6	0	0
May 2008	3	0	0
Jun 2008	9	0	0
Jul 2008	2	0	0
Aug 2008	8	0	0
Sep 2008	5	0	0
Oct 2008	1	0	0
Nov 2008	5	0	2
Dec 2008	4	0	2
Jan 2009	3	0	1
Feb 2009	1	0	3
Mar 2009	4	0	19
Apr 2009	6	0	5
May 2009	3	0	5
Jun 2009	1	0	1
Jul 2009	5	0	1
Aug 2009	3	0	1
Sep 2009	2	0	1
Oct 2009	2	0	0
Nov 2009	5	0	1
Dec 2009	5	0	1
Jan 2010	2	0	2
Feb 2010	1	0	3
Mar 2010	4	0	3
Apr 2010	11	0	5
May 2010	8	0	1
Jun 2010	6	0	5
Jul 2010	3	0	1
Aug 2010	2	0	2
Oct 2010	7	0	4
Nov 2010	10	0	0
Dec 2010	5	0	2
Jan 2011	6	0	3
Feb 2011	4	0	1
Mar 2011	2	0	2
Apr 2011	9	0	2
May 2011	4	0	0
Jun 2011	4	0	0
Jul 2011	24	0	0
Aug 2011	17	0	1
Sep 2011	16	0	0
Oct 2011	25	0	4
Nov 2011	30	0	3
Dec 2011	15	0	5
Jan 2012	24	0	3
Feb 2012	15	0	2
Mar 2012	21	0	1
Apr 2012	22	0	6
May 2012	35	0	4
Jun 2012	21	0	4
Jul 2012	28	0	18
Aug 2012	14	0	2
Sep 2012	24	0	4
Oct 2012	31	0	3
Nov 2012	28	0	1
Dec 2012	14	0	10
Jan 2013	15	0	2
Feb 2013	28	0	0
Mar 2013	31	0	5
Apr 2013	32	0	6
May 2013	27	0	6
Jun 2013	14	0	1
Jul 2013	13	0	6
Aug 2013	8	0	0
Sep 2013	26	0	3
Oct 2013	20	0	3
Nov 2013	26	0	2
Dec 2013	13	0	0
Jan 2014	36	0	2
Feb 2014	23	0	1
Mar 2014	29	0	6
Apr 2014	21	0	4
May 2014	14	0	3
Jun 2014	17	0	1
Jul 2014	20	0	1
Aug 2014	20	0	1
Sep 2014	17	0	4
Oct 2014	35	0	4
Nov 2014	30	0	3
Dec 2014	15	0	1
Jan 2015	23	0	5
Feb 2015	21	0	12
Mar 2015	25	0	4
Apr 2015	9	0	2
May 2015	16	0	7
Jun 2015	6	0	0
Jul 2015	8	0	1
Aug 2015	4	0	4
Sep 2015	12	0	1
Oct 2015	16	0	35
Nov 2015	15	0	1
Dec 2015	7	0	3
Jan 2016	6	0	6
Feb 2016	14	0	6
Mar 2016	14	0	2
Apr 2016	8	0	6
May 2016	9	0	3
Jun 2016	12	0	8
Jul 2016	13	1	10
Aug 2016	9	1	7
Sep 2016	9	0	15
Oct 2016	7	0	11
Nov 2016	8	0	1
Dec 2016	9	0	3
Jan 2017	11	0	5
Feb 2017	6	0	4
Mar 2017	8	0	1
Apr 2017	6	0	5
May 2017	7	0	4
Jun 2017	18	0	3
Jul 2017	10	0	3
Aug 2017	8	0	0
Sep 2017	34	0	3
Oct 2017	16	0	1
Nov 2017	16	0	5
Dec 2017	10	0	0
Jan 2018	14	0	1
Feb 2018	24	0	4
Mar 2018	6	0	1
Apr 2018	12	0	0
May 2018	30	0	2
Jun 2018	24	0	2
Jul 2018	36	0	2
Aug 2018	14	0	4
Sep 2018	20	0	4
Oct 2018	16	0	10
Nov 2018	10	0	3
Dec 2018	14	0	2
Jan 2019	5	0	2
Feb 2019	13	0	3
Mar 2019	12	0	11
Apr 2019	12	0	7
May 2019	24	0	5
Jun 2019	22	0	12
Jul 2019	12	0	8
Aug 2019	10	0	3
Sep 2019	6	0	2
Oct 2019	18	0	5
Nov 2019	10	0	3
Dec 2019	8	0	9
Jan 2020	6	0	3
Feb 2020	12	0	9
Mar 2020	8	0	5
Apr 2020	12	0	1
May 2020	18	0	23
Jun 2020	6	0	4
Jul 2020	12	0	4
Aug 2020	18	0	8
Sep 2020	40	0	8
Oct 2020	26	0	8
Nov 2020	26	0	3
Dec 2020	30	0	3
Jan 2021	34	0	5
Feb 2021	18	0	8
Mar 2021	12	0	2
Apr 2021	0	0	7
May 2021	0	0	4
Jul 2021	0	0	2
Aug 2021	0	0	9
Sep 2021	0	0	10
Oct 2021	10	0	16
Nov 2021	11	0	9
Dec 2021	18	0	0
Jan 2022	20	0	6
Feb 2022	26	0	5
Mar 2022	20	0	4
Apr 2022	10	0	6
May 2022	38	0	10
Jun 2022	44	0	4
Jul 2022	18	0	2
Aug 2022	50	0	8
Sep 2022	38	0	22
Oct 2022	44	0	5
Nov 2022	22	0	7
Dec 2022	14	0	3
Jan 2023	26	0	4
Feb 2023	66	0	4
Mar 2023	8	0	3
Apr 2023	20	0	9
May 2023	16	0	7
Jun 2023	14	0	2
Jul 2023	16	0	9
Aug 2023	14	0	7
Sep 2023	22	0	7
Oct 2023	10	0	3
Nov 2023	23	0	4
Dec 2023	98	0	5
Jan 2024	92	0	0
Feb 2024	52	0	1
Mar 2024	40	0	1
Apr 2024	44	0	1
May 2024	68	0	0
Jun 2024	28	0	1
Jul 2024	36	0	1
Aug 2024	32	0	0
Sep 2024	44	0	1
Oct 2024	32	0	0
Total	3649	2	811

Log in using your username and password

Main menu

Log in using your username and password

You are here

Online download statistics by month:

Online download statistics by month: March 1999 to October 2024

Read the full text or download the PDF:

Log in using your username and password