It may seem a mighty task to produce a book dealing with most of the major aspects of neurobiological research and its relevance to disease, particularly when that book weighs in at less than 21lbs. This volume, however, goes a long way in achieving these admirable goals.

The volume is dedicated to Tom Sears who has recently retired from the Chair of the Sobell Department of Neurophysiology, at the Institute of Neurology in London. The editors have gathered together an impressive list of contributors, and it is a tribute to Tom Sears that most …