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Magnetic Resonance in Multiple Sclerosis.

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    Magnetic Resonance in Multiple Sclerosis.Edited by d h miller, j kesselring, w i mcdonald, d w paty, and a j thompson. (Pp 200; £50.00). Published by Cambridge University Press, Cambridge, 1997. ISBNO-52 1-47325-X.

    This book comprises 171 editorial pages divided into three chapters. It seems more directed towards clinical neurologists rather than neuroradiologists or basic scientists, as its summary suggests, since it is largely concise and simplistic in its explanation of terminology and technology. It attempts to comprehensively consider both the benefits and limitations of MR in multiple sclerosis and its role in clinical practice and is largely successful in its aims. It has an impressive list of authors who undoubtedly represent some of the most senior researchers in the field who have assessed the impact of MR on the management of multiple sclerosis and the insights into pathogenesis it has provided as well as more predictable subjects such as the distribution and morphology of lesions in the disease and differential diagnosis. I found one of the most useful sections was the explanation of terms which tend to bring uninitiated neurologists such as myself into a cold sweat such as FLAIR, FSE, ADC, and TE, which are explained in a brief and uncomplicated manner. In addition the review of the role of MR in the ever increasing number of clinical trials which place so much emphasis on this technique as a surrogate marker of disease activity was illuminating. This book is well written and beautifully illustrated, as one would expect, but my only question mark would be the place of this text in the library of a general neurologist. The competition is great and the number of textbooks which consider not only MR but the entire clinical picture of multiple sclerosis seems to grow by the month. Therefore I just wonder whether most would see the details on MR provided in such tomes as MacAlpine’s or Raines’ multiple sclerosis sufficient without investing a further £50.