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This book covers most aspects relating to the neurobiology of Parkinson’s disease and closely related conditions and arose from the 11th International Symposium on Parkinson’s disease held in March 1994. These meetings are held every three years and are recognised as one of the major international symposia on these conditions and this book is filled with contributions from current international figures in this field. Nearly half the book is devoted to epidemiological, biochemical, and physiopathological aspects of Parkinson’s disease and related conditions. reflecting current interests worldwide. Inevitably, it seems that collections of papers arising from a large meeting contain anomalies of structure, and this one is no exception. However, one benefit may be balance in terms of representation of current views and this is achieved in the representation of both sides of the “genes or environment” question. Clinical aspects focus particularly on the “Parkinson plus” syndromes and dementia in Parkinson’s disease, with separate sections on autonomic disorders, and neuroimaging, and the last section deals with therapeutic aspects. Although this section is probably now more out of date than any of the others, there are chapters on most of the major pharmacological treatments and there is a particularly helpful outline of therapeutic controversies. This section also covers thalamotomies, pallidotomies, and subthalamic stimulation, but strangely there is no separate chapter on neural transplantation. Overall this is a useful and interesting book for anyone with an interest in extrapyramidal syndromes.
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