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Post-traumatic stimulus suppressible myoclonus of peripheral origin
  1. Frédéric Assal,
  2. Michel R Magistris,
  3. François J G Vingerhoets
  1. Clinique et Policlinique de Neurologie, H U G, Geneva, Switzerland
  1. Dr FJG Vingerhoets, Policlinique de Neurologie, HUG, 24 rue Micheli-du-Crest, 1211 Genève 14, Switzerland. Telephone 0041 22 372 8318; fax 0041 22 372 8332.


A patient is described who presented with myoclonus of the first dorsal interosseus muscle of the right foot. This myoclonus occurred 18 months after trauma of the cutaneous branch of the deep peroneal nerve on the dorsal aspect of the foot. Tactile stimulation in the dermatome of this nerve, or an anaesthetic block of the deep peroneal nerve stopped the myoclonus. The different innervation between the efferent motor activity responsible for the movements and the sensory afference suppressing it points firmly towards involvement of central connections. However, abolition of the movement by anaesthesia suggests the presence of a peripheral ectopic generator. This finding confirms that focal myoclonus can have its origin in the peripheral nervous system and may be modulated by sensory inputs.

  • post-traumatic movement disorders
  • myoclonus
  • peripheral nerve
  • plasticity

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