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Untreated hepatitis C may provoke myasthenia gravis
  1. Department of Neurology
  2. Middlesbrough General Hospital
  3. Ayresome Green Road, Middlesbrough TS5 5AZ
  1. Dr PJ Reading, Department of Neurology, Royal Victoria Infirmary, Queen Victoria Road, Newcastle-upon-Tyne NE1 4LP, UK

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Recent reports have suggested a causative link between the use of interferon (INFα) treatment in chronic hepatitis C virus (HCV) infections and the development of myasthenia gravis.1 2 This presents something of a conundrum given that low dose INFα has been advocated as a treatment for myasthenia and seems to be well tolerated in those with established disease.3 Further confusion arises from the well established finding that untreated HCV infection itself leads to a markedly increased risk of developing various autoimmune conditions including rheumatoid arthritis, autoimmune thyroid disease, systemic lupus erythematosus, and polymyositis.4 A recent …

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