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Untreated hepatitis C may provoke myasthenia gravis
  1. P J READING,
  2. P K NEWMAN
  1. Department of Neurology
  2. Middlesbrough General Hospital
  3. Ayresome Green Road, Middlesbrough TS5 5AZ
  1. Dr PJ Reading, Department of Neurology, Royal Victoria Infirmary, Queen Victoria Road, Newcastle-upon-Tyne NE1 4LP, UK

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Recent reports have suggested a causative link between the use of interferon (INFα) treatment in chronic hepatitis C virus (HCV) infections and the development of myasthenia gravis.1 2 This presents something of a conundrum given that low dose INFα has been advocated as a treatment for myasthenia and seems to be well tolerated in those with established disease.3 Further confusion arises from the well established finding that untreated HCV infection itself leads to a markedly increased risk of developing various autoimmune conditions including rheumatoid arthritis, autoimmune thyroid disease, systemic lupus erythematosus, and polymyositis.4 A recent …

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