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Neurological picture
Cortical sclerosis presenting with dementia as a sequel of rapid correction of hyponatraemia
  1. CHRISTINE LEBRUN,
  2. PIERRE THOMAS,
  3. MARCEL CHATEL
  1. Service De Neurologie
  2. Service D’explorations Fonctionnelles Du Systeme Nerveux (Pr Dolisi)
  3. Service De Neurochirurgie (Pr Grellier)
  4. Service De Radiologie (Pr Padovani), Hôpital Pasteur, 30 Voie Romaine, Nice, France
  1. Dr Christine Lebrun, Service de Neurologie. Hôpital Pasteur, 30 Voie Romaine, BP 69. 06002. Nice. Cedex 1. France. Telephone 0033 4 92 03 77 44; fax 0033 4 92 03 79 07
  1. MARIE NOELLE MAGNIE
  1. Service De Neurologie
  2. Service D’explorations Fonctionnelles Du Systeme Nerveux (Pr Dolisi)
  3. Service De Neurochirurgie (Pr Grellier)
  4. Service De Radiologie (Pr Padovani), Hôpital Pasteur, 30 Voie Romaine, Nice, France
  1. Dr Christine Lebrun, Service de Neurologie. Hôpital Pasteur, 30 Voie Romaine, BP 69. 06002. Nice. Cedex 1. France. Telephone 0033 4 92 03 77 44; fax 0033 4 92 03 79 07
  1. PHILIPPE PAQUIS
  1. Service De Neurologie
  2. Service D’explorations Fonctionnelles Du Systeme Nerveux (Pr Dolisi)
  3. Service De Neurochirurgie (Pr Grellier)
  4. Service De Radiologie (Pr Padovani), Hôpital Pasteur, 30 Voie Romaine, Nice, France
  1. Dr Christine Lebrun, Service de Neurologie. Hôpital Pasteur, 30 Voie Romaine, BP 69. 06002. Nice. Cedex 1. France. Telephone 0033 4 92 03 77 44; fax 0033 4 92 03 79 07
  1. STÉPHANE CHANALET
  1. Service De Neurologie
  2. Service D’explorations Fonctionnelles Du Systeme Nerveux (Pr Dolisi)
  3. Service De Neurochirurgie (Pr Grellier)
  4. Service De Radiologie (Pr Padovani), Hôpital Pasteur, 30 Voie Romaine, Nice, France
  1. Dr Christine Lebrun, Service de Neurologie. Hôpital Pasteur, 30 Voie Romaine, BP 69. 06002. Nice. Cedex 1. France. Telephone 0033 4 92 03 77 44; fax 0033 4 92 03 79 07

https://doi.org/10.1136/jnnp.66.5.685

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    (A) (right) axial; (left) coronal enhanced T1 weighted MRI. Gyriform cortical enhancement: cortical laminar sclerosis. On the coronal scan, postoperative changes and enhancing tumour remnants of a pituitary macroadenoma can be seen. (B) Global cortical hypofixation on brain HMPAO scintigraphy.

    We report the case of a previously healthy 53 year old woman who became chronically vegetative after transphenoidal pituitary surgery complicated by hyponatraemia. She was admitted to our hospital because of a speech disturbance and confusion. Ten …

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