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Continuous drop type of orthostatic hypotension
  1. TAKANORI YOKOTA,
  2. KAZUTO MITANI,
  3. YUKINOBU SAITO
  1. Department of Neurology
  2. Third Department of Internal Medicine,Tokyo Medical and Dental University, Tokyo 113, Japan
  3. Department of Neurology, Tokyo Metropolitan Neurological Hospital,Tokyo 183, Japan
  1. Dr Takanori Yokota, Department of Neurology, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan. Telephone +81-3-5803-5234; fax +81-3-5808-0169.
  1. TOSHIYUKI ONIKI
  1. Department of Neurology
  2. Third Department of Internal Medicine,Tokyo Medical and Dental University, Tokyo 113, Japan
  3. Department of Neurology, Tokyo Metropolitan Neurological Hospital,Tokyo 183, Japan
  1. Dr Takanori Yokota, Department of Neurology, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan. Telephone +81-3-5803-5234; fax +81-3-5808-0169.
  1. MICHIYUKI HAYASHI
  1. Department of Neurology
  2. Third Department of Internal Medicine,Tokyo Medical and Dental University, Tokyo 113, Japan
  3. Department of Neurology, Tokyo Metropolitan Neurological Hospital,Tokyo 183, Japan
  1. Dr Takanori Yokota, Department of Neurology, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan. Telephone +81-3-5803-5234; fax +81-3-5808-0169.

https://doi.org/10.1136/jnnp.67.2.255a

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    Orthostatic hypotension has usually been evaluated for 2–10 minutes after standing.1 2 Multiple system atrophy (MSA: Shy-Drager syndrome) is one of the neurodegeneratative diseases which show marked orthostatic hypotension. We studied changes of blood pressure for more than 20 minutes after standing in 30 patients with MSA.

    The patients lay down on a tilting table, and an intravenous cannula was introduced into the cubital vein more than 30 minutes before the 25 minute test of 60° head up tilt. Blood pressure and heart rate were recorded every minute with an automatic sphygmomanometer. Patients could clearly be classified into two groups in terms of the time taken to …

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