Randomised, double blind, placebo controlled study of interferon β-1a in relapsing-remitting multiple sclerosis analysed by area under disability/time curves

Clarence Liu; Lance D Blumhardt

doi:10.1136/jnnp.67.4.451

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Paper

Randomised, double blind, placebo controlled study of interferon β-1a in relapsing-remitting multiple sclerosis analysed by area under disability/time curves

Online download statistics by month:

Online download statistics by month: September 1999 to March 2024

	Abstract	Full	Pdf
Sep 1999	45	66	22
Oct 1999	31	35	20
Nov 1999	21	20	3
Dec 1999	4	13	3
Jan 2000	4	6	1
Feb 2000	6	6	1
Mar 2000	0	10	7
Apr 2000	1	4	6
May 2000	12	8	2
Jun 2000	3	9	2
Jul 2000	3	5	3
Aug 2000	4	4	2
Sep 2000	1	3	3
Oct 2000	6	5	3
Nov 2000	6	14	9
Dec 2000	1	6	5
Jan 2001	0	5	1
Feb 2001	0	7	2
Mar 2001	1	13	1
Apr 2001	1	12	5
May 2001	2	9	0
Jun 2001	0	13	2
Jul 2001	0	6	5
Aug 2001	1	6	2
Sep 2001	2	10	1
Oct 2001	2	12	1
Nov 2001	0	12	4
Dec 2001	1	2	1
Jan 2002	1	9	1
Feb 2002	3	14	1
Mar 2002	2	9	2
Apr 2002	0	4	2
May 2002	0	7	0
Jun 2002	1	5	0
Jul 2002	2	10	3
Aug 2002	0	6	3
Sep 2002	1	13	1
Oct 2002	2	13	6
Nov 2002	1	4	7
Dec 2002	0	6	7
Jan 2003	1	4	6
Feb 2003	2	7	9
Mar 2003	0	4	4
Apr 2003	2	4	4
May 2003	0	9	9
Jun 2003	3	9	1
Jul 2003	2	13	11
Aug 2003	4	3	1
Sep 2003	2	7	7
Oct 2003	1	7	6
Nov 2003	0	5	13
Dec 2003	1	10	9
Jan 2004	1	2	1
Feb 2004	2	5	4
Mar 2004	1	9	5
Apr 2004	0	3	3
May 2004	0	3	3
Jun 2004	4	7	2
Jul 2004	44	51	10
Aug 2004	34	42	7
Sep 2004	20	39	7
Oct 2004	13	42	5
Nov 2004	6	40	5
Dec 2004	4	23	7
Jan 2005	9	43	17
Feb 2005	12	37	7
Mar 2005	11	30	12
Apr 2005	3	22	9
May 2005	2	26	9
Jun 2005	7	19	9
Jul 2005	3	9	3
Aug 2005	3	14	11
Sep 2005	4	16	14
Oct 2005	8	19	6
Nov 2005	3	22	10
Dec 2005	4	10	3
Jan 2006	2	15	5
Feb 2006	7	14	4
Mar 2006	3	14	9
Apr 2006	6	7	3
May 2006	2	6	4
Jun 2006	3	7	6
Jul 2006	3	7	3
Aug 2006	1	5	1
Sep 2006	1	7	2
Oct 2006	0	11	3
Nov 2006	0	9	4
Dec 2006	1	8	4
Jan 2007	3	6	7
Feb 2007	5	7	6
Mar 2007	8	14	9
Apr 2007	4	2	4
May 2007	5	2	1
Jun 2007	2	3	2
Jul 2007	2	1	3
Aug 2007	3	5	3
Sep 2007	3	2	1
Oct 2007	5	5	2
Nov 2007	6	4	4
Dec 2007	2	5	4
Jan 2008	0	1	1
Feb 2008	5	10	5
Mar 2008	5	2	3
Apr 2008	3	3	1
May 2008	1	0	1
Jun 2008	0	1	1
Jul 2008	2	0	1
Aug 2008	8	4	4
Sep 2008	9	3	1
Oct 2008	2	2	2
Nov 2008	6	11	4
Dec 2008	2	2	0
Jan 2009	3	0	1
Feb 2009	7	0	0
Mar 2009	6	1	1
Apr 2009	2	0	2
May 2009	3	2	3
Jun 2009	1	1	0
Jul 2009	5	0	1
Aug 2009	7	1	1
Sep 2009	3	0	1
Oct 2009	6	0	2
Nov 2009	12	3	4
Dec 2009	8	1	1
Jan 2010	3	1	2
Feb 2010	2	1	0
Mar 2010	4	0	3
Apr 2010	4	3	2
May 2010	3	2	0
Jun 2010	6	1	3
Jul 2010	5	0	0
Aug 2010	2	2	2
Sep 2010	2	0	1
Oct 2010	4	2	2
Nov 2010	12	2	1
Dec 2010	4	0	1
Jan 2011	1	0	0
Feb 2011	1	10	2
Mar 2011	7	4	6
Apr 2011	7	2	0
May 2011	4	3	2
Jun 2011	2	0	1
Jul 2011	5	0	0
Aug 2011	7	1	0
Sep 2011	3	1	3
Oct 2011	11	3	5
Nov 2011	11	2	1
Dec 2011	5	5	1
Jan 2012	10	10	3
Feb 2012	6	3	3
Mar 2012	6	4	2
Apr 2012	9	10	2
May 2012	4	8	6
Jun 2012	8	13	2
Jul 2012	8	11	7
Aug 2012	4	2	10
Sep 2012	6	8	4
Oct 2012	10	5	6
Nov 2012	13	13	6
Dec 2012	14	16	8
Jan 2013	14	12	3
Feb 2013	14	11	5
Mar 2013	5	11	5
Apr 2013	11	13	6
May 2013	11	20	8
Jun 2013	4	5	14
Jul 2013	7	4	8
Aug 2013	8	3	5
Sep 2013	10	6	2
Oct 2013	2	7	1
Nov 2013	3	3	5
Dec 2013	3	7	2
Jan 2014	5	5	3
Feb 2014	3	11	4
Mar 2014	7	9	3
Apr 2014	9	19	10
May 2014	6	24	8
Jun 2014	3	19	4
Jul 2014	11	12	4
Aug 2014	4	14	6
Sep 2014	13	39	9
Oct 2014	3	38	4
Nov 2014	9	15	8
Dec 2014	9	8	4
Jan 2015	11	4	2
Feb 2015	3	3	4
Mar 2015	4	12	6
Apr 2015	3	16	7
May 2015	3	17	4
Jun 2015	10	19	7
Jul 2015	1	18	3
Aug 2015	6	10	6
Sep 2015	5	13	6
Oct 2015	2	3	3
Nov 2015	6	14	7
Dec 2015	5	9	5
Jan 2016	10	4	2
Feb 2016	10	10	3
Mar 2016	7	6	8
Apr 2016	6	11	8
May 2016	11	11	4
Jun 2016	6	10	8
Jul 2016	3	9	2
Aug 2016	4	2	1
Sep 2016	8	5	4
Oct 2016	6	15	2
Nov 2016	2	9	1
Dec 2016	4	10	0
Jan 2017	3	6	2
Feb 2017	7	5	6
Mar 2017	1	6	1
Apr 2017	1	10	2
May 2017	1	6	1
Jun 2017	5	10	2
Jul 2017	3	3	0
Aug 2017	8	8	1
Sep 2017	15	15	2
Oct 2017	12	12	5
Nov 2017	23	15	4
Dec 2017	24	20	5
Jan 2018	9	5	0
Feb 2018	19	11	1
Mar 2018	12	8	5
Apr 2018	22	14	2
May 2018	22	21	4
Jun 2018	19	19	5
Jul 2018	17	11	3
Aug 2018	13	11	3
Sep 2018	9	5	4
Oct 2018	13	9	1
Nov 2018	3	3	2
Dec 2018	26	16	9
Jan 2019	4	4	1
Feb 2019	9	7	3
Mar 2019	4	5	5
Apr 2019	5	5	8
May 2019	6	6	5
Jun 2019	4	4	8
Jul 2019	7	5	7
Aug 2019	13	5	5
Sep 2019	11	9	4
Oct 2019	14	14	5
Nov 2019	4	4	5
Dec 2019	10	4	4
Jan 2020	7	7	4
Feb 2020	11	7	6
Mar 2020	4	4	6
Apr 2020	11	11	5
May 2020	9	7	3
Jun 2020	8	8	5
Jul 2020	9	9	2
Aug 2020	9	9	8
Sep 2020	15	13	1
Oct 2020	23	23	10
Nov 2020	24	22	8
Dec 2020	18	16	3
Jan 2021	26	23	12
Feb 2021	14	12	6
Mar 2021	13	13	1
Apr 2021	10	6	5
May 2021	18	16	9
Jun 2021	9	9	2
Jul 2021	8	8	5
Aug 2021	9	10	6
Sep 2021	15	14	7
Oct 2021	14	12	18
Nov 2021	5	4	10
Dec 2021	4	4	2
Jan 2022	15	12	5
Feb 2022	18	10	5
Mar 2022	14	11	2
Apr 2022	21	19	2
May 2022	30	27	13
Jun 2022	20	20	3
Jul 2022	18	15	8
Aug 2022	24	24	1
Sep 2022	21	17	6
Oct 2022	38	32	9
Nov 2022	14	13	5
Dec 2022	7	5	1
Jan 2023	7	6	4
Feb 2023	23	23	1
Mar 2023	4	4	3
Apr 2023	4	4	6
May 2023	6	6	5
Jun 2023	7	7	4
Jul 2023	2	2	5
Aug 2023	13	7	9
Sep 2023	8	8	3
Oct 2023	18	19	14
Nov 2023	20	20	8
Dec 2023	65	8	4
Jan 2024	21	1	0
Feb 2024	33	1	1
Mar 2024	93	0	0
Total	2328	2862	1266

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