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IgG anti-GQ1b positive acute ataxia without ophthalmoplegia
  1. Masahiro Moria,
  2. Satoshi Kuwabaraa,
  3. Michiaki Kogab,
  4. Mayumi Asahinaa,
  5. Kazue Ogawaraa,
  6. Takamichi Hattoria,
  7. Nobuhiro Yukib
  1. aDepartment of Neurology, Chiba University School of Medicine, Chiba, Japan, bDepartment of Neurology, Dokkyo University School of Medicine, Tochigi, Japan
  1. Dr Masahiro Mori, Department of Neurology, Chiba University School of Medicine, 1–8–1 Inohana, Chuo-ku, Chiba, 260–8670 Japan. Telephone 0081 43 222 7171 ext 5414; fax 0081 43 226 2160; email.morim{at}


IgG anti-GQ1b antibody was present in a patient with acute ataxia and areflexia without ophthalmoplegia or elementary sensory loss. Sensory nerve conduction studies and somatosensory evoked potentials were normal, but postural body sway analysis showed dysfunction of the proprioceptive afferent system. The clinical presentation and laboratory results for this patient resemble those of Miller Fisher syndrome, except for the lack of ophthalmoplegia. This case may represent part of an IgG anti-GQ1b syndrome.

  • ataxia
  • Miller Fisher syndrome
  • anti-GQ1b antibody

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