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Magnetic resonance imaging and vertebral artery dissection
  1. B R BLOEM,
  2. G J LAMMERS
  1. Department of Neurology
  2. Department of Radiology, Leiden University Medical Centre, The Netherlands
  1. Dr Bastiaan R Bloem, Department of Neurology, Leiden University Medical Centre, PO Box 9600, 2300 RC Leiden, The Netherlands. Telephone 0031 71 5262134; fax 0031 71 5248253; email bloem{at}rullf2.medfac.leidenuniv.nl
  1. M A VAN BUCHEM
  1. Department of Neurology
  2. Department of Radiology, Leiden University Medical Centre, The Netherlands
  1. Dr Bastiaan R Bloem, Department of Neurology, Leiden University Medical Centre, PO Box 9600, 2300 RC Leiden, The Netherlands. Telephone 0031 71 5262134; fax 0031 71 5248253; email bloem{at}rullf2.medfac.leidenuniv.nl

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Since the advent of advanced radiological modalities such as MRI and magnetic resonance angiography (MRA), dissections of cervical arteries are increasingly recognised as a common cause of stroke in young adults. Auer et al 1recently advocated MRA as the initial diagnostic tool for vertebral artery dissection. Conventional angiography might be avoided altogether in subjects with a suspicious history and MRA images suggestive of a dissection (double lumen or mural haematoma).1 The sensitivity of MRA for the diagnosis of vertebral artery dissection was only 20% in one study, but the specificity was excellent (100%).2 The sensitivity was considerably better in the hands of Auer et al,1 but in this study the specificity (true negative rate in subjects free of disease) was not considered because all patients had vertebral artery dissection. The following case report illustrates that care must be taken to avoid false positive results when using MRA for the diagnosis of vertebral artery dissection.

A 47 year old male pilot suddenly experienced clumsiness and slight loss of strength in the right arm and leg during a long distance flight, while he stooped forward. During the following hours, he developed a global headache without irradiation to the neck, but the other symptoms gradually diminished. Prior history was unremarkable, except for a 3 hour period of horizontal diplopia which suddenly developed 3 months earlier. He had never smoked. Family history was negative for cardiovascular disorders. The patient later confessed that he had recently picked up the habit of gargling his throat with toothpaste twice a day, always with his …

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