Article Text
Correspondence
Prospective, population based studies of cavernous malformations are needed
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In their welcome systematic review of supratentorial cavernous malformations and epilepsy, Moran et al 1 illustrate the pitfalls of regarding the prognosis of a disease in selected case series as representative of its natural history.2 Studies of cavernous malformation prognosis have usually lacked clear inception cohorts with respect to mode of presentation and treatment. Referral filter bias has so often restricted ascertainment by tertiary referral centres, and further selection bias has made the prognosis seem worse …