Hedonistic homeostatic dysregulation in patients with Parkinson's disease on dopamine replacement therapies

G Giovannoni; J D O'Sullivan; K Turner; A J Manson; A J L Lees

doi:10.1136/jnnp.68.4.423

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Hedonistic homeostatic dysregulation in patients with Parkinson's disease on dopamine replacement therapies

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Online download statistics by month: March 2000 to February 2023

	Abstract	Full	Pdf
Mar 2000	57	59	26
Apr 2000	45	75	33
May 2000	27	19	3
Jun 2000	7	4	4
Jul 2000	7	10	7
Aug 2000	4	10	4
Sep 2000	13	15	6
Oct 2000	8	17	7
Nov 2000	9	24	3
Dec 2000	0	5	10
Jan 2001	5	8	4
Feb 2001	6	8	6
Mar 2001	9	25	23
Apr 2001	9	14	5
May 2001	1	18	5
Jun 2001	1	2	0
Jul 2001	6	12	3
Aug 2001	5	8	3
Sep 2001	4	9	7
Oct 2001	5	14	1
Nov 2001	10	14	4
Dec 2001	7	7	3
Jan 2002	11	31	4
Feb 2002	16	14	3
Mar 2002	2	23	8
Apr 2002	8	15	1
May 2002	5	21	2
Jun 2002	9	14	3
Jul 2002	10	15	18
Aug 2002	3	10	14
Sep 2002	15	14	10
Oct 2002	2	8	10
Nov 2002	5	10	6
Dec 2002	17	31	19
Jan 2003	8	11	14
Feb 2003	13	22	6
Mar 2003	6	17	13
Apr 2003	2	3	3
May 2003	7	18	9
Jun 2003	3	10	4
Jul 2003	6	30	11
Aug 2003	6	11	10
Sep 2003	10	23	9
Oct 2003	7	21	7
Nov 2003	5	15	18
Dec 2003	8	21	23
Jan 2004	16	14	24
Feb 2004	11	15	22
Mar 2004	13	25	31
Apr 2004	12	16	18
May 2004	7	14	8
Jun 2004	10	27	11
Jul 2004	50	86	10
Aug 2004	66	112	21
Sep 2004	56	94	16
Oct 2004	35	79	22
Nov 2004	25	149	41
Dec 2004	65	108	35
Jan 2005	50	135	28
Feb 2005	41	103	31
Mar 2005	46	132	43
Apr 2005	32	106	30
May 2005	17	100	27
Jun 2005	24	85	42
Jul 2005	71	147	75
Aug 2005	41	130	55
Sep 2005	36	90	37
Oct 2005	50	106	36
Nov 2005	51	136	60
Dec 2005	43	91	32
Jan 2006	36	142	49
Feb 2006	46	119	44
Mar 2006	38	125	48
Apr 2006	49	75	36
May 2006	54	71	38
Jun 2006	46	76	50
Jul 2006	43	77	30
Aug 2006	42	95	39
Sep 2006	56	87	53
Oct 2006	56	125	56
Nov 2006	63	93	43
Dec 2006	33	76	36
Jan 2007	54	85	43
Feb 2007	47	96	44
Mar 2007	59	125	50
Apr 2007	101	30	35
May 2007	80	31	33
Jun 2007	65	35	28
Jul 2007	65	56	48
Aug 2007	69	22	29
Sep 2007	71	31	33
Oct 2007	93	38	38
Nov 2007	70	33	34
Dec 2007	76	17	21
Jan 2008	77	24	31
Feb 2008	82	45	38
Mar 2008	111	45	49
Apr 2008	79	18	19
May 2008	59	20	23
Jun 2008	56	18	21
Jul 2008	74	29	13
Aug 2008	131	25	25
Sep 2008	66	24	18
Oct 2008	48	21	25
Nov 2008	76	22	19
Dec 2008	58	22	20
Jan 2009	49	10	15
Feb 2009	43	16	19
Mar 2009	68	21	23
Apr 2009	91	30	26
May 2009	66	13	18
Jun 2009	72	12	17
Jul 2009	50	12	17
Aug 2009	54	5	15
Sep 2009	47	4	13
Oct 2009	94	14	14
Nov 2009	90	16	12
Dec 2009	69	4	7
Jan 2010	66	18	13
Feb 2010	43	5	13
Mar 2010	117	20	17
Apr 2010	67	12	8
May 2010	51	9	7
Jun 2010	55	29	29
Jul 2010	49	20	11
Aug 2010	48	22	15
Sep 2010	45	18	18
Oct 2010	48	7	9
Nov 2010	72	16	9
Dec 2010	40	8	9
Jan 2011	38	19	6
Feb 2011	57	19	11
Mar 2011	64	14	20
Apr 2011	79	8	10
May 2011	53	12	12
Jun 2011	56	4	5
Jul 2011	51	4	8
Aug 2011	53	22	9
Sep 2011	46	7	8
Oct 2011	79	14	21
Nov 2011	104	11	15
Dec 2011	48	37	27
Jan 2012	67	42	18
Feb 2012	47	26	24
Mar 2012	43	35	26
Apr 2012	65	33	51
May 2012	87	40	32
Jun 2012	57	33	36
Jul 2012	63	26	25
Aug 2012	51	24	22
Sep 2012	63	34	34
Oct 2012	71	41	50
Nov 2012	62	61	33
Dec 2012	79	33	26
Jan 2013	97	62	30
Feb 2013	77	41	30
Mar 2013	69	53	28
Apr 2013	75	50	34
May 2013	80	54	29
Jun 2013	55	29	26
Jul 2013	42	26	18
Aug 2013	42	30	21
Sep 2013	57	29	12
Oct 2013	63	40	29
Nov 2013	62	31	28
Dec 2013	46	21	27
Jan 2014	55	19	34
Feb 2014	56	30	22
Mar 2014	89	37	35
Apr 2014	58	38	31
May 2014	67	23	20
Jun 2014	59	28	15
Jul 2014	70	38	15
Aug 2014	85	40	12
Sep 2014	85	46	27
Oct 2014	79	38	23
Nov 2014	235	30	18
Dec 2014	137	25	11
Jan 2015	135	27	18
Feb 2015	120	19	19
Mar 2015	185	52	24
Apr 2015	235	51	10
May 2015	191	46	22
Jun 2015	191	37	21
Jul 2015	152	31	8
Aug 2015	149	26	10
Sep 2015	146	37	27
Oct 2015	75	25	22
Nov 2015	103	28	19
Dec 2015	134	36	15
Jan 2016	117	27	17
Feb 2016	132	16	24
Mar 2016	71	26	26
Apr 2016	86	30	17
May 2016	51	31	12
Jun 2016	43	21	21
Jul 2016	47	101	16
Aug 2016	49	36	14
Sep 2016	67	53	25
Oct 2016	133	63	19
Nov 2016	73	57	17
Dec 2016	88	35	9
Jan 2017	115	124	12
Feb 2017	53	186	35
Mar 2017	40	268	25
Apr 2017	31	116	24
May 2017	40	70	17
Jun 2017	33	52	16
Jul 2017	56	47	16
Aug 2017	65	51	117
Sep 2017	89	57	103
Oct 2017	74	42	124
Nov 2017	92	58	121
Dec 2017	54	26	128
Jan 2018	79	35	145
Feb 2018	135	43	116
Mar 2018	106	44	11
Apr 2018	131	51	20
May 2018	130	67	52
Jun 2018	71	33	157
Jul 2018	62	36	140
Aug 2018	45	29	85
Sep 2018	74	34	124
Oct 2018	91	41	170
Nov 2018	101	43	167
Dec 2018	87	55	125
Jan 2019	68	30	148
Feb 2019	81	43	161
Mar 2019	86	45	149
Apr 2019	109	68	151
May 2019	98	54	197
Jun 2019	61	41	134
Jul 2019	39	22	154
Aug 2019	70	36	150
Sep 2019	73	41	208
Oct 2019	79	47	90
Nov 2019	84	56	85
Dec 2019	77	45	85
Jan 2020	73	45	79
Feb 2020	63	31	74
Mar 2020	87	63	92
Apr 2020	80	40	103
May 2020	52	25	81
Jun 2020	49	37	43
Jul 2020	42	24	47
Aug 2020	62	50	34
Sep 2020	89	45	32
Oct 2020	101	59	30
Nov 2020	117	76	18
Dec 2020	67	44	19
Jan 2021	95	77	27
Feb 2021	83	65	20
Mar 2021	71	51	28
Apr 2021	121	90	29
May 2021	103	84	22
Jun 2021	78	79	32
Jul 2021	70	70	30
Aug 2021	89	86	24
Sep 2021	104	104	27
Oct 2021	144	95	32
Nov 2021	115	84	33
Dec 2021	130	109	30
Jan 2022	139	105	26
Feb 2022	103	79	21
Mar 2022	163	129	40
Apr 2022	154	116	23
May 2022	130	108	32
Jun 2022	125	101	28
Jul 2022	88	72	13
Aug 2022	86	67	12
Sep 2022	167	137	40
Oct 2022	165	114	15
Nov 2022	136	105	23
Dec 2022	120	109	29
Jan 2023	171	151	27
Feb 2023	136	105	14
Total	17963	12834	9387

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