What clinical features are most useful to distinguish definite multiple system atrophy from Parkinson's disease?

G K Wenning; Y Ben-Shlomo; A Hughes; S E Daniel; A Lees; N P Quinn

doi:10.1136/jnnp.68.4.434

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What clinical features are most useful to distinguish definite multiple system atrophy from Parkinson's disease?

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	Abstract	Full	Pdf
Mar 2000	121	191	116
Apr 2000	105	172	72
May 2000	31	55	16
Jun 2000	19	50	20
Jul 2000	13	34	19
Aug 2000	13	29	14
Sep 2000	14	25	13
Oct 2000	10	30	14
Nov 2000	5	19	11
Dec 2000	6	30	21
Jan 2001	10	20	12
Feb 2001	4	28	11
Mar 2001	9	24	4
Apr 2001	4	24	11
May 2001	6	53	9
Jun 2001	8	32	10
Jul 2001	0	29	5
Aug 2001	6	28	9
Sep 2001	2	31	9
Oct 2001	8	25	5
Nov 2001	7	40	8
Dec 2001	3	16	7
Jan 2002	2	26	7
Feb 2002	9	36	6
Mar 2002	4	33	4
Apr 2002	9	27	7
May 2002	3	45	7
Jun 2002	6	26	1
Jul 2002	7	28	9
Aug 2002	6	50	22
Sep 2002	4	25	28
Oct 2002	4	23	15
Nov 2002	3	22	8
Dec 2002	13	41	38
Jan 2003	12	42	24
Feb 2003	5	12	13
Mar 2003	12	41	37
Apr 2003	8	14	14
May 2003	7	36	39
Jun 2003	8	26	19
Jul 2003	0	21	19
Aug 2003	5	18	18
Sep 2003	7	23	17
Oct 2003	8	29	8
Nov 2003	6	25	14
Dec 2003	4	23	14
Jan 2004	5	15	19
Feb 2004	9	38	28
Mar 2004	11	25	28
Apr 2004	18	32	27
May 2004	7	26	21
Jun 2004	9	23	19
Jul 2004	54	91	37
Aug 2004	48	77	21
Sep 2004	31	65	20
Oct 2004	24	91	44
Nov 2004	32	60	42
Dec 2004	32	67	28
Jan 2005	18	55	35
Feb 2005	45	61	33
Mar 2005	32	66	37
Apr 2005	36	60	21
May 2005	30	55	22
Jun 2005	10	38	27
Jul 2005	12	64	33
Aug 2005	27	52	34
Sep 2005	21	54	33
Oct 2005	31	104	42
Nov 2005	20	58	37
Dec 2005	14	42	28
Jan 2006	23	58	34
Feb 2006	21	66	21
Mar 2006	16	79	31
Apr 2006	33	71	32
May 2006	55	54	34
Jun 2006	26	38	20
Jul 2006	24	45	27
Aug 2006	31	39	22
Sep 2006	41	47	30
Oct 2006	43	58	33
Nov 2006	41	50	37
Dec 2006	27	38	20
Jan 2007	29	34	24
Feb 2007	23	49	22
Mar 2007	37	43	20
Apr 2007	52	16	16
May 2007	51	17	13
Jun 2007	37	20	19
Jul 2007	27	18	16
Aug 2007	34	14	12
Sep 2007	23	11	11
Oct 2007	58	9	20
Nov 2007	39	14	19
Dec 2007	25	9	11
Jan 2008	34	15	21
Feb 2008	19	6	10
Mar 2008	43	11	44
Apr 2008	47	10	26
May 2008	26	5	8
Jun 2008	19	10	17
Jul 2008	21	8	10
Aug 2008	37	12	16
Sep 2008	43	10	14
Oct 2008	35	7	7
Nov 2008	24	12	11
Dec 2008	22	9	6
Jan 2009	21	4	10
Feb 2009	16	8	11
Mar 2009	41	9	15
Apr 2009	39	7	12
May 2009	25	13	12
Jun 2009	23	4	6
Jul 2009	19	10	8
Aug 2009	17	20	9
Sep 2009	30	11	9
Oct 2009	36	6	8
Nov 2009	28	5	6
Dec 2009	31	1	5
Jan 2010	26	4	9
Feb 2010	22	3	4
Mar 2010	13	6	9
Apr 2010	18	9	9
May 2010	29	11	6
Jun 2010	12	10	10
Jul 2010	25	3	7
Aug 2010	11	5	8
Sep 2010	16	7	8
Oct 2010	17	6	10
Nov 2010	15	16	16
Dec 2010	25	2	4
Jan 2011	10	4	6
Feb 2011	33	8	11
Mar 2011	18	13	12
Apr 2011	22	8	8
May 2011	23	1	5
Jun 2011	27	2	5
Jul 2011	30	4	3
Aug 2011	37	5	12
Sep 2011	20	7	4
Oct 2011	37	4	8
Nov 2011	26	17	17
Dec 2011	14	16	10
Jan 2012	28	27	13
Feb 2012	14	24	16
Mar 2012	24	26	14
Apr 2012	17	20	18
May 2012	35	33	18
Jun 2012	26	18	16
Jul 2012	31	21	24
Aug 2012	32	18	15
Sep 2012	25	24	18
Oct 2012	46	33	25
Nov 2012	42	51	23
Dec 2012	27	19	15
Jan 2013	50	29	16
Feb 2013	25	36	14
Mar 2013	37	37	17
Apr 2013	46	31	35
May 2013	18	24	18
Jun 2013	23	28	15
Jul 2013	29	22	11
Aug 2013	30	23	9
Sep 2013	44	27	15
Oct 2013	33	33	17
Nov 2013	47	41	29
Dec 2013	28	23	21
Jan 2014	31	31	18
Feb 2014	24	21	13
Mar 2014	30	29	20
Apr 2014	41	28	12
May 2014	40	34	27
Jun 2014	22	27	12
Jul 2014	25	57	11
Aug 2014	19	36	10
Sep 2014	22	44	6
Oct 2014	36	19	13
Nov 2014	24	9	15
Dec 2014	12	6	5
Jan 2015	31	6	8
Feb 2015	56	12	14
Mar 2015	79	30	15
Apr 2015	24	8	6
May 2015	27	17	11
Jun 2015	25	11	8
Jul 2015	34	31	8
Aug 2015	124	28	12
Sep 2015	34	18	19
Oct 2015	58	17	8
Nov 2015	48	24	6
Dec 2015	53	26	6
Jan 2016	56	31	12
Feb 2016	56	10	9
Mar 2016	40	18	8
Apr 2016	39	16	7
May 2016	33	17	13
Jun 2016	25	16	5
Jul 2016	39	17	10
Aug 2016	40	23	9
Sep 2016	40	27	10
Oct 2016	47	34	18
Nov 2016	36	31	9
Dec 2016	45	12	9
Jan 2017	53	17	7
Feb 2017	23	16	26
Mar 2017	22	32	15
Apr 2017	9	27	10
May 2017	12	29	9
Jun 2017	17	25	14
Jul 2017	35	26	18
Aug 2017	25	11	7
Sep 2017	42	24	11
Oct 2017	58	30	19
Nov 2017	63	47	21
Dec 2017	44	24	8
Jan 2018	25	13	11
Feb 2018	51	31	13
Mar 2018	44	16	7
Apr 2018	81	39	12
May 2018	44	22	17
Jun 2018	42	22	11
Jul 2018	59	19	23
Aug 2018	74	44	17
Sep 2018	86	56	15
Oct 2018	114	68	28
Nov 2018	110	76	30
Dec 2018	73	51	30
Jan 2019	96	62	37
Feb 2019	71	58	13
Mar 2019	114	80	26
Apr 2019	153	133	37
May 2019	97	77	25
Jun 2019	72	60	77
Jul 2019	98	80	98
Aug 2019	106	90	89
Sep 2019	65	51	101
Oct 2019	99	75	46
Nov 2019	60	43	10
Dec 2019	62	50	10
Jan 2020	59	39	12
Feb 2020	76	34	28
Mar 2020	82	44	12
Apr 2020	30	20	6
May 2020	73	50	12
Jun 2020	104	76	9
Jul 2020	136	100	16
Aug 2020	123	79	17
Sep 2020	125	99	14
Oct 2020	168	126	11
Nov 2020	134	94	11
Dec 2020	156	118	24
Jan 2021	159	98	22
Feb 2021	99	49	25
Mar 2021	129	54	25
Apr 2021	87	47	27
May 2021	73	52	20
Jun 2021	40	40	19
Jul 2021	54	53	16
Aug 2021	59	59	15
Sep 2021	53	53	28
Oct 2021	47	35	45
Nov 2021	51	30	38
Dec 2021	77	60	19
Jan 2022	53	36	27
Feb 2022	45	38	21
Mar 2022	70	65	33
Apr 2022	53	45	26
May 2022	110	89	36
Jun 2022	85	76	43
Jul 2022	69	35	24
Aug 2022	67	50	16
Sep 2022	88	70	31
Oct 2022	85	66	23
Nov 2022	94	47	23
Dec 2022	75	61	17
Jan 2023	68	46	20
Feb 2023	63	48	10
Mar 2023	73	43	22
Apr 2023	90	53	37
May 2023	60	31	20
Jun 2023	40	32	10
Jul 2023	46	44	28
Aug 2023	46	36	19
Sep 2023	83	76	27
Oct 2023	122	107	28
Nov 2023	108	33	26
Dec 2023	210	15	10
Jan 2024	88	8	1
Feb 2024	114	2	1
Mar 2024	278	3	1
Apr 2024	112	10	3
May 2024	124	8	2
Jun 2024	96	3	0
Jul 2024	111	13	2
Aug 2024	62	5	2
Sep 2024	136	5	4
Total	12859	10198	5412

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